Tailbacks formed on the A563 Lubbesthorpe Way near Meridian Park in Leicester after the crash which occurred during the evening rush hour. As a result several adjoining routes also experienced some delay.
Emergency services were called to the incident at around 5.30pm. The collision left both carriageways of the road partially blocked.
The northbound lane between Fosse Park and Meridian Leisure Park was still congested at 8pm.
Several vehicles were involved in the crash but it is not believed there were any serious injuries.